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The workes of that famous Chirurgion Ambrose Parey

science and technology

An Inquiry into the Causes and Effects of the Variolae Vaccinae

Title page of Jenner’s groundbreaking ‘Inquiry into the Causes and Effects of the Variolae Vaccinae’, first published in 1798. In it Jenner included case studies and observation drawings to back up his theory that cowpox could be used as a vaccination against smallpox.

An Inquiry into the Causes and Effects of the Variolae Vaccinae

Left image: Observational drawing of case studies conducted by Jenner on whether a cowpox vaccination would stop the development of smallpox on a 5 year old boy. Middle image: Observational drawing of case studies conducted by Jenner on whether a cowpox vaccination would stop the development of smallpox on a 6 year old boy. Right

An Inquiry into the Causes and Effects of the Variolae Vaccinae

Jenner’s observational comments in his book ‘An Inquiry into the Causes and Effects of the Variolae Vaccinae’, 1798. In it he observed how James Phipps, an 8 year old boy was given cow pox from the pus of the milkmaid Sarah Nelmes. He was then given the more deadly smallpox virus and never developed the

Harvey’s Motion of the Heart and Blood in Animals

An illustration from Harvey’s ‘Motion of the Heart and Blood in Animals’ illustrating an experiment to show how blood is pumped around the body and that the valves in the veins will only allow the blood to flow in one direction. This disproved Galen who had said the liver created fresh blood.

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